The Sierra Platinum Service for generating peak-calls for replicated ChIP-seq experiments

TitleThe Sierra Platinum Service for generating peak-calls for replicated ChIP-seq experiments
Publication TypeJournal Article
Year of Publication2018
AuthorsWiegreffe, Daniel, Müller Lydia, Steuck Jens, Zeckzer Dirk, and Stadler Peter F.
JournalBMC Research Notes
Date Published07/2018
Type of ArticleResearch Note
KeywordsChIP-seq, Histone modifications, Peak-caller, Replicate analysis
Abstract Objective Sierra Platinum is a fast and robust peak-caller for replicated ChIP-seq experiments with visual quality-control and -steering. The required computing resources are optimized but still may exceed the resources available to researchers at biological research institutes. Results Sierra Platinum Service provides the full functionality of Sierra Platinum: using a web interface, a new instance of the service can be generated. Then experimental data is uploaded and the computation of the peaks is started. Upon completion, the results can be inspected interactively and then downloaded for further analysis, at which point the service terminates.
URLhttps://bmcresnotes.biomedcentral.com/articles/10.1186/s13104-018-3633-x
DOI10.1186/s13104-018-3633-x
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