English
DeutschSierra platinum: a fast and robust peak-caller for replicated ChIP-seq experiments with visual quality-control and -steering
| Title | Sierra platinum: a fast and robust peak-caller for replicated ChIP-seq experiments with visual quality-control and -steering |
| Publication Type | Journal Article |
| Year of Publication | 2016 |
| Authors | Müller, Lydia, Wiegreffe Daniel, Farman Mariam, and Zeckzer Dirk |
| Journal | BMC Bioinformatics |
| Volume | 17 |
| Issue | 1 |
| Start Page | 1 |
| Pagination | 1--13 |
| Date Published | 09/2016 |
| ISSN | 1471-2105 |
| Abstract | Histone modifications play an important role in gene regulation. Their genomic locations are of great interest. Usually, the location is measured by ChIP-seq and analyzed with a peak-caller. Replicated ChIP-seq experiments become more and more available. However, their analysis is based on single-experiment peak-calling or on tools like PePr which allows peak-calling of replicates but whose underlying model might not be suitable for the conditions under which the experiments are performed. |
| URL | http://dx.doi.org/10.1186/s12859-016-1248-6 |
| DOI | 10.1186/s12859-016-1248-6 |
| Refereed Designation | Refereed |
Undefined
