English
DeutschiDotter - an interactive dot plot viewer
| Title | iDotter - an interactive dot plot viewer |
| Publication Type | Conference Proceedings |
| Year of Conference | 2017 |
| Authors | Wiegreffe, Daniel, Hausdorf Alrik, Zänker Sebastian, and Zeckzer Dirk |
| Conference Name | 25. International Conference in Central Europe on Computer Graphics, Visualization and Computer Vision WSCG 2017 |
| Pagination | 117-124 |
| Date Published | 08/2017 |
| Conference Location | Pilsen, Czech Republic |
| ISBN Number | 978-80-86943-49-7 |
| Keywords | Bioinformatics Visualization, Dot Plots, Tabular Data, User Interfaces |
| Abstract | Bioinformaticians judge the likelihood of the overall RNA secondary structure based on comparing its base pair probabilities. These probabilities can be calculated by various tools and are frequently displayed using dot plots for further analysis. However, most tools produce only static dot plot images which restricts possible interactions to the capabilities of the respective viewers (mostly PostScript-viewers). Moreover, this approach does not scale well with larger RNAs since most PostScript viewers are not designed to show a huge number of elements and have only legacy support for PostScript. Therefore, we developed iDotter, an interactive tool for analyzing RNA secondary structures. iDotter overcomes the previously described limitations providing multiple interaction mech- anisms facilitating the interactive analysis of the displayed data. According to the biologists and bioinformaticians that regularly use out interactive dot plot viewer, iDotter is superior to all previous approaches with respect to facilitating dot plot based analysis of RNA secondary structures. |
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